Crop Biotech Update


A weekly summary of world developments in agri-biotech for developing countries, produced by the Global Knowledge Center on Crop Biotechnology, International Service for the Acquisition of Agri-biotech Applications SEAsiaCenter (ISAAA), and AgBiotechNet 
August 9, 2002

In This Issue:

Investments Needed to Create Technologies
New Agri-biotech Products Could Enhance Consumer Acceptance
US Proposes New Systems Regarding GM Crops
Japan's Bio Plaza 21 To Provide Biotech Info
Update on World Summit on Sustainable Development
Hepa B Immunization Through Potatoes
Public to Choose Issues for UK GM Debate 
ANNOUNCEMENT: Pocket Ks 7 and 8 Available on-Line

INVESTMENTS NEEDED TO CREATE TECHNOLOGIES 

Given the necessary funding, conventional crop breeding, as well as emerging technologies based on molecular biology, genetic engineering and natural resource management, will continue to improve productivity in the coming decades.

This is the major point raised by Jikun Huang, Carl Pray and Scott Rozelle in an article on "Enhancing the crops to feed the poor" published in the August 8, 2002 issue of Nature. The authors are from the Chinese Academy of Sciences, Rutgers University, and University of California, respectively.

The article explores how technology can help the developing world to meet its food needs in the 21st century. It discusses the constraints that are holding back food production and assesses the technologies that are available and hold promise in the future.

The agricultural economists say that for future generations, "the scientist and policy makers must create an environment conducive to creative and rapid technological change". A research-friendly environment depends on the following critical elements: clear priorities, right mix of funding and research effort between conventional plant breeding and modern genetic technology, and the right combination of genetics and agronomic-based research. 

In the short term, Jikun Huang and colleagues opine that conventional plant breeding still has many important roles to play in developing countries. Over the long run, however, agricultural research will depend on high-technology methods. Ultimately, government commitment to support continued research on agriculture is essential to ensure food security. 

The full paper is available at: http://www.nature.com/cgi-taf/DynaPage.taf?file=/
nature/journal/v418/n6898/full/nature01015_fs.html&content_filetype=pdf
 




US PROPOSES NEW SYSTEMS REGARDING GM CROPS 

The US Office of Science and Technology Policy (OSTP) announced proposed federal actions to update field test requirements for biotech-derived plants and to establish early food safety assessments for new proteins produced by such plants.

Federal Register, Vol. 67, Number 149 states that "these measures are aimed at preventing low levels of biotechnology-derived genes and gene products from being found in commercial seed, commodities, and processed food and feed until appropriate safety standards can be met".

Under this new system, the Food and Drug Administration will review data packages while crops are still in small acreage plots and determine whether there are allergenicity or toxicity concerns. The complete proposal is available at: http://frwebgate.access.gpo.gov/cgi-bin/getdoc.cgi?
dbname=2002_register&docid=02-19746-filed
.

Meanwhile, Reuters reports that the US Department of Agriculture may create a voluntary system to verify if shipments of US corn, soybeans and other crops were genetically altered. It would be a voluntary federal program to ensure that conventional grains, oilseeds, rice and seed products were not inadvertently exposed to genetically modified crops. 

Under the planned program, companies could choose to detail to the USDA how they keep their products separate from gene-altered crops at all levels of the food chain--from farm harvesting equipment to storage bins to processing plants. Federal inspectors would review a company's system and verify that minimum requirements for crop production, handling and processing were followed.

The new system would verify "the process and not the final product", the USDA said. Participating companies would be able to market their crops as "USDA Process Verified". A similar voluntary program could be created for seeds. However, US seed exporters could have the option of including a USDA-approved label on their biotech-free products. 




UPDATE ON WORLD SUMMIT ON SUSTAINABLE DEVELOPMENT 

Leaders of more than 100 countries, joined by tens of thousands of delegates, journalists, and industry and NGO representatives, will attend the World Summit on Sustainable Development (WSSD) set for Johannesburg, South Africa from 26 August - 4 September 2002. The WSSD marks the 10-year anniversary of the Rio Earth Summit. It will focus the world's attention and direct action towards meeting difficult challenges in today's world.

Ten years after the 1992 Earth Summit in Rio, the Johannesburg Summit presents an exciting opportunity for today's leaders to adopt concrete steps and quantifiable targets for implementing Agenda 21. After all, the best strategies are only as good as their implementation.

During the 1992 Rio Summit, a number of important conclusions were reached relating to sustainable development and two major conventions were signed - the Convention on Climate Change and the Convention on Biological Diversity. Furthermore, participating governments and other interested parties accepted Agenda 21, a program of actions to promote sustainable development. At this meeting, there was also consensus that developed countries would allocate resources and technology to developing countries to enable them to build their capacity in a more effective way. 

The WSSD will not renegotiate Agenda 21 but will carry out a serious review of progress, lessons learned, and assess its implementation over the last 10 years. There are expected to be three main outcomes from the summit, United Nations organizers say. 

* A political declaration, where heads of state and government commit to taking the action needed to make sustainable development a reality 

* A plan of implementation, negotiated by governments, which sets out in more detail the action that needs to be taken in specific areas 

* Commitments by governments and all other stakeholders to a broad range of partnership activities that will implement sustainable development at the national, regional and international level

For more details about the WSSD, go to http://www.johannesburgsummit.org/index.html. The International Service for the Acquisition of Agri-Biotech Applications (ISAAA) position paper can be downloaded at http://www.isaaa.org/kc/WSSD/Worldsummit.htm




PUBLIC TO CHOOSE ISSUES FOR UK GM DEBATE 

"The Government wants a genuinely open and balanced discussion on GM", said UK Environment Secretary Margaret Beckett. She further said, "there is clearly a wide range of views on this issue and we want to ensure all voices are heard".

The debate will start in autumn and would have three components: a public debate; a review of scientific issues relating to GM; and a study into the overall costs and benefits of GM crops which will be carried out by the Prime Minister's strategy Unit.

Secretary Beckett said that the Ministry shares the Agriculture and Environment Biotechnology Commission's analysis that the public debate will help deepen public understanding of all issues about GM. It was further stated that, "the Government wants to provide people with the opportunity to debate the issues openly and reach their own judgments".

The full story can be downloaded from the UK Department for Environment Food and Rural Affairs website at http://www.defra.gov.uk/news/2002/020726a.htm  




NEW AGRI-BIOTECH PRODUCTS COULD ENHANCE CONSUMER ACCEPTANCE

Over the next several years, crop biotech could be applied to develop crops important to expanding world populations with enhanced nutritional traits. These products should further enhance consumer acceptance of the technology. This is according to a paper by Dr. Susan Harlander of BIOrational Consultants, which appeared in the Journal of American College of Nutrition, Vol. 21, No. 3, 2002.

Harlander's paper entitled "The Evolution of Modern Agriculture and Its Future with Biotechnology" discusses that genetic modification has been going on for years through conventional breeding, radiation breeding and wide crosses. In a short time, crops developed through biotechnology have had an enormous impact on our food supply and on modern agriculture. 

Harlander's paper states that given today's situation in population growth and agriculture production, conventional breeding would not be enough to sustainably meet the needed yield increases. "Biotechnology is an important tool in addition to all other tools to produce a food supply that will be sustainable in the long run and will be able to meet these needs in the future."

Biotechnology crops are the most rapidly adopted technology in the history of US agriculture. Benefits from GM crops include resistance to pests, resistance to herbicides that allows for easier management of crops and reduced pesticide use. 

Harlander further discusses that since their introduction, GM crops have been required to undergo extensive food and environmental safety evaluations prior to commercialization. There has been no confirmed adverse report to date.

Labeling of GM products is another controversial issue and highlights the difference in views of Americans and Europeans. Harlander contends that labeling and identity preservation issues could become irrelevant when new GM products come out. This may include foods with allergens removed; improved taste, texture and aroma; and better keeping quality.

The original paper is available online at http://www.jacn.org/cgi/reprint/21/suppl_3/161S.pdf. 




JAPAN'S BIO PLAZA 21 TO PROVIDE BIOTECH INFO 

The Tokyo-based Life and Bio Plaza 21 Information Center, which aims to give neutral and science-based information to the general public has recently been recognized as a non-profit organization.

In order to ensure its neutrality, the center submitted an application for a non-profit organization status to the Tokyo Metropolitan Government Office earlier this year. Preparations for the establishment of the center were initiated under the auspices of the Japan Association of Bioindustries Executives. 

While maintaining its socially neutral position, Bio Plaza 21 aims to function as a forum for deepening mutual understanding and the open, two-way exchange of opinions between people with differing standpoints, concerning the impacts that the application of biotechnology could have on society and industry.

Furthermore, while providing a forum for the discussion of biotechnology by such means as setting up a homepage, publishing a newsletter, and planning events in which anyone can participate, regardless of age, the center aims to form linkages extending throughout the society.

The executive officers of Bio Plaza 21 are expected to be: Director-General: Dr. Kunihisa Ota (Emeritus Professor, Tokyo University), Deputy Director-General: Dr. Mieko Oshima (Vice-Principal, Tohoku University of Community Service and Science), and Managing Director: Dr. Takeshi Mayama (Advisor, Meiji Seika Kaisha, Ltd.).




HEPA B IMMUNIZATION THROUGH POTATOES

Hepatitis B is a severe liver disease including liver failure and cancer. Aside from being a sexually transmitted disease, it is a hardy virus that can exist in almost any surface for one month. It is easier to catch than HIV and over 5,000 people die every year from Hepatitis B-related liver disease.

A highly effective and safe hepatitis B vaccine was licensed in the US in 1986. However, the product is technology-intensive and is therefore expensive especially for developing countries. A research team led by Qingxian Kong of the Department of Immunology, New York, decided to use a potato in producing hepatitis B surface antigen (HBsAg). Transgenic plants have the advantage of having low production costs and the technology development cost can be fully borne at the outset of the project.

Mice fed with the raw potatoes produced HBsAg-specific serum antibodies that exceeded the protective level. However, cooking substantially reduced the immunogenicity of the vaccine. Raw potatoes are unpalatable for people but HBsAg-transgenic tomatoes are currently being evaluated.

The information about hepatitis B came from http://www.immunize.org/catg.d/p4115.htm. The research on transgenic potatoes came from www.pnas.org/cgi/doi/10.1073/pnas.191617598. 




ANNOUNCEMENT: POCKET KS 7 AND 8 AVAILABLE ON-LINE

Do you need a handy guide on labeling genetically modified foods, and the Cartagena Protocol on Biosafety? The Global Knowledge Center on Crop Biotechnology has made available on-line two of its latest Pocket K (Knowledge) series. Pocket Ks are packaged information on crop biotechnology products and related issues that are written in an to easy to understand style. Download the two materials and other Pocket Ks for free at http://www.isaaa.org/kc/Services/
Media/PocketK_download.htm
.

 

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