Crop Biotech Update


A weekly summary of world developments in agri-biotech for developing countries, produced by the Global Knowledge Center on Crop Biotechnology, International Service for the Acquisition of Agri-biotech Applications SEAsiaCenter (ISAAA), and AgBiotechNet 
September 13, 2002

In This Issue:

WSSD Plan of Implementation Available
First IRRI-Philrice Field Evaluation of GM Rice
Plant Science Industry Can Contribute to Sustainable Development
Legal Aspects of Biotechnology Tackled at Biolaw 2002
Draft Code of Conduct on Biotechnology
Announcements
Impact of Herbicide Tolerant Soybeans
New K Sheet
Strategy for Maintaining Gene Banks
Virtual Exhibit of Banana Project
Nigeria Budgets US$19.4 M Yearly for Biotech
International Conference on Technology in Sustainable Agriculture
Byrne: Biotech Offers Huge Possibilities for Safe Food
International Conference on S&T Ethics
Gene Targeting in Rice
Rice Gene Machine Workshop

WSSD PLAN OF IMPLEMENTATION AVAILABLE

One of the key documents produced from the recently concluded World Summit on Sustainable Development (WSSD) is already available. The advanced, unedited text of the WSSD Plan of Implementation was posted last September 4, 2002.

The Plan strongly reaffirms commitment to the Rio principles, the full implementation of Agenda 21 and the Programme for the Further Implementation of Agenda 21. It also signifies commitment to undertake concrete actions and measures at all levels. Efforts will also be made to promote the integration of the three components of sustainable development - economic development, social development, and environment protection. 

It was also recognized that the implementation of the outcomes of the Summit should benefit and involve all sectors. Good governance, nationally and internationally, was stated as essential for sustainable development. At the domestic level, the basis for sustainable development are sound environmental, social, and economic policies, democratic institutions responsive to the needs of the people, the rule of law, anti-corruption measures, gender equality, and an enabling environment for investment.

The Plan has sections on poverty eradication, changing unsustainable patterns of consumption and production, protecting and managing the natural resource base of economic and social development, sustainable development in a globalizing world, health and sustainable development, sustainable development of small island developing States, sustainable development for Africa, other regional initiatives, means of implementation, and institutional framework for sustainable development. 

The text may be downloaded at http://www.johannesburgsummit.org/html/documents/
summit_docs/plan_final1009.doc
 




PLANT SCIENCE INDUSTRY CAN CONTRIBUTE TO SUSTAINABLE DEVELOPMENT

"Our industry is determined to help advance sustainable development through the use and development of products" said Syngenta's Chairman of the Board of Directors, Heinz Imhof during a speech at the World Summit on Sustainable Development (WSSD). He started by acknowledging that UN Secretary General, Kofi Annan, identified agriculture as one of the key target areas where concrete results must be obtained. Chairman Imhof's speech was composed of five messages which are as follows:

The development of sustainable agricultural systems is fundamental to world food security and poverty alleviation. There is a need to double food supply to meet the needs of an increasing population, longer life expectancy and higher Gross Domestic Product per capita. The needs of over 1.1 billion people living in poverty also have to be addressed.

To promote sustainable agriculture and development, the plant science industry will contribute significantly. Imhof said that the plant science industry's products will continue to support farmers in the key areas of yield protection, crop enhancement and quality improvement. Products will also need less water, tolerate saline land and contain additional nutrients.

Product stewardship, through responsible and sustainable use of products, is another key component for progress. An example is the commitment to work on the safety evaluation of genetically enhanced crops.

The fourth message is that knowledge and technology transfer using public-private partnerships can make a real difference in the promotion of sustainable agriculture. He said that farmers are able to improve their productivity and incomes by themselves in a sustainable manner if they have access to products, information and technology.

Lastly, stakeholder dialogue based on open and transparent risk/benefit analysis is essential for success. This dialogue must be based on facts and science.

Syngenta is a world leading agribusiness company. Chairman Imhof's speech at the WSSD can be downloaded at http://www.syngenta.com/en/media/article.asp?article_id=238 




DRAFT CODE OF CONDUCT ON BIOTECHNOLOGY

A preliminary draft of an ""International Code of Conduct on Biotechnology as it Affects the Conservation and Utilization of Plant Genetic Resources" is available at the Food and Agriculture Organization (FAO) of the United Nations. Surveys were conducted among FAO Members and a wide range of relevant stakeholders throughout the world.

Most members who supported the work considered FAO and its Commission on Genetic Resources for Food and Agriculture to be an appropriate forum. A number of them pointed to the complementarity between genetic resources for food and agriculture and biotechnologies. There was broad support that the main objective of the Code should remain as "to maximize the positive effects of biotechnologies and minimize undesired effects and possible risks".

It was generally emphasized that the Code should be in harmony with relevant international agreements such as the Cartagena Biosafety Protocol and the International Undertaking on Plant Genetic Resources for Food and Agriculture. Most respondents felt that the Code could provide a framework for promoting appropriate biotechnologies, capacity-building, and international cooperation for the management of biotechnologies for genetic resources for food and agriculture. It was also stated that the recent developments in gene technologies would need a fresh approach in developing the Code. 

The Draft Code of Conduct is available at ftp://ext-ftp.fao.org/ag/cgrfa/cgrfa9/r9w18e.pdf  




IMPACT OF HERBICIDE TOLERANT SOYBEANS

A study was conducted by the George Morris Center to determine the impact of Glyphosate Tolerant (GT) soybeans in Ontario. The impacts were classified as agronomic, economic and environmental.

Farmers using GT technology had made, on the average, 1.7 fewer passes over their fields for herbicide application. Further, they used less of the implements usually associated with soil erosion. Producers who use GT were also leaving more residue on the ground which is beneficial to the environment.

In terms of profitability, data from the study can not give an overall indication on the effect of GT partially because the respondents did not know their costs or do not keep records in a way that would allow them to answer the necessary questions. However, producers perceived that GT technology saves labor and fuel and lowers herbicide costs.

In terms of environmental impact, Ontario producers were split on whether GT technology has positive or negative impact on biodiversity.

The George Morris Centre is a Canada-wide, not-for-profit organization. As an independent think-tank, the Centre provides industry decision makers with critical information and analysis on issues affecting the Canadian agri-food sector. The study can be downloaded at http://www.georgemorris.org/
CBIFINALReport0702CCB.pdf
 




STRATEGY FOR MAINTAINING GENE BANKS

One of the ways of making genetic materials available is through gene banks such as what the Consultative Group on International Agricultural Research (CGIAR) maintains. The organization has 11 genebanks which conserve over 660,000 plant or seed samples. CGIAR is an association of public and private members supporting a system of 16 Future Harvest Centers that work in more than 100 countries to mobilize cutting-edge science to reduce hunger and poverty, improve human nutrition and health, and protect the environment. The plant or seed samples in the CGIAR genebanks are crops grown mainly by poor people or staple food crops grown throughout the world.

A serious concern in this endeavor is the mismatch between the long-term needs of maintaining the genebanks and the availability of funds only at an annual basis. It is estimated that the annual cost of conserving and distributing the genetic material presently in the CGIAR genebanks is US$ 5.7 million per year. The funding needs for these core genebank services could be met by setting aside a fund of US$ 149 million invested at a real interest rate of 4% per annum. However, these estimates are sensitive to a number of factors including crop composition and size of holdings, the number of samples distributed annually to the genebanks, the technology of germplasm storage, the rate of interest used to calculate the present value of distant future costs and various conservation protocols.

The report is available at the website of IFPRI, one of the CGIAR research centers, at http://www.ifpri.org/pubs/cp/sgrpfh.htm  




NIGERIA BUDGETS US$19.4 M YEARLY FOR BIOTECH 

The Federal Government of Nigeria will spend N2.5 billion (around $19.4 million) a year for three years on biotechnology, through its National Biotechnology Development Agency (NABDA). 

President Olusegun Obasanjo said "I am convinced that the only reliable way forward for rapid biotechnological development in the country is a close and sustained government/ researchers/ industry collaboration." Obasanjo called on the science community for a "a well thought out and focused agenda that would meet the country's needs for biotech goods and services within the next 10 years".

He stressed that the vision and intention of setting up NABDA was that "Nigeria should, as a matter of priority initiate appropriate steps to explore the use of biotechnology for the benefit of Nigerians and thus ensure that Nigeria becomes one of the international leaders in biotechnology."

Nigeria's biotechnology development program objectives include: 

* ensuring self reliance in the development and production of biotechnology-derived products and services critical to national economy; 
* ensuring access to and benefit from safe, ethical, and profitable uses of biotechnology-based products and services; 
* ensuring that biotechnology is profitably applied to government's stewardship such as assurance of high quality health services, food security, environmental protection, and safety; and
* ensuring sustenance in the development and application of acceptable
and profitable technologies through strategic investments in biotech R&D to support/enhance innovation and accelerate economic development. 




BYRNE : BIOTECH OFFERS HUGE POSSIBILITIES FOR SAFE FOOD 

David Byrne, European Union Commissioner for Health and Consumer Protection, said that biotechnology had the potential to offer huge possibilities for future innovation in terms of cheaper, safer and more cost-effective production, and hinted strongly that the moratorium on genetically modified organisms (GMOs) must end.

"The proposals presented by the Commission for traceability and labeling of GM-food and GM-feed provide a sound and balanced platform on which to build," he said at the Informal Agriculture Council in Nyborg. "It is important that innovation
in the biotech field is not impeded by emotional reactions and apprehension based on inadequate or biased information. There can however, be no question of compromising public health or the environment", noted Byrne.

However, Byrne went on to warn that there was no point talking about innovation in the abstract if progress was not made on starting new GMO authorizations and ending the so-called moratorium.

He told the gathering of EU farm ministers that it was time for the EU to give people the choice whether they wanted to consume GM food or not - implying an end to the current moratorium.

This would end an effective ban on growing GM crops. He noted that a law laying down tougher criteria than in the past to allow farmers to grow GM crops was due to come into force in mid-October, which is seen by some as setting the scene for ending the ban. "We cannot continue forever with this moratorium. It must end at some stage," Byrne said. 




GENE TARGETING IN RICE 

Researchers have found a rapid way of finding the function of specific genes in rice, one of the world's most vital staples. Previously, assigning function to rice genes was a hit and miss affair because researchers could only create mutants by randomly targeting genes through chemical treatment or the use of highly mobile pieces of DNA called transposons.

In a paper in the October issue of Nature Biotechnology, Japanese researchers have developed a method for targeting genes specifically that works efficiently in rice.

To demonstrate their approach, Shigeru Iida and colleagues at the National Institute for Basic Biology in Japan decided to target the native rice waxy gene, which encodes an enzyme that influences the quality and quantity of rice grains. Knowing that DNA sequences with the same sequence tend to recombine within the genome, the Japanese team set out to determine whether introduction of an artificial DNA molecule with the same sequence as the Waxy gene could disrupt its structure. Hence, producing visible effects on the targeted plants, allowing the investigators to infer gene function.

Before they could do this, however, they had to make the recombination process much more efficient in rice. This was accomplished by making the DNA introduction method more efficient and refining the ways of selecting plants containing successfully targeted Waxy genes. Around 1 in 100 plants contained a disrupted Waxy gene, which is an unprecedented efficiency for gene targeting in higher plants. Because the selection approach is independent of the nature of the gene, the strategy could be more widely applied to other genes and has the potential to be used in many other crops.

More details are available in the paper "Efficient recombination in rice" by Rie Terada, Hiroko Urawa, Yoshishige Inagaki , Kazuo Tsugane, and Shigeru Iida. Email Shigeru Iida, National Institute for Basic Biology, Okazaki 444-8585, Japan at shigiida@nibb.ac.jp for additional information. 




FIRST IRRI-PHILRICE FIELD EVALUATION OF GM RICE 

The International Rice Research Institute (IRRI) Bulletin reports that transgenic rice variety IR72 with the Xa21 gene (TT103) has shown good agronomic performance in Muņoz, Philippines. These materials were examined last week at Muņoz by IRRI-Philippine Rice Research Institute (PhilRice) experts and members of the Institute Biosafety Committee (IBC). The material was developed previously at IRRI and has shown excellent protection against available races of bacterial blight in Asia under screenhouse conditions at IRRI (1998-99). 

It took several years to transfer this material for open-field evaluation, which has been coordinated by Dr.Rhodora Aldemita at PhilRice. The transgenic rice was developed under supervision of Dr. Swapan Datta. Currently, several elite indica lines including materials for hybrid rice are being developed with Xa21 and Bt genes for bacterial blight and stem borer resistance. Following IBC and the National Committee on Biosafety of the Philippines guidelines and cooperation, IRRI-PhilRice will continue such field testing with other materials in the future. 

For more information, email Dr. Swapan Datta at s.datta@cgiar.org 




LEGAL ASPECTS OF BIOTECHNOLOGY TACKLED AT BIOLAW 2002

Scientists and lawyers exchanged knowledge and opinions on the legal implications of biotechnology in a conference held in Bangkok, Thailand last 3-5 September.

In tandem with the rapid development of biotechnology, legal implications are getting increasingly complicated. However, scientists and lawyers seem to exist in separate environments. Thus, Biolaw 2002 was principally organized to promote understanding of the legal aspects of biotechnology applications and "bridge the gap between the two separate worlds - the world of scientists and the world of lawyers", according to Dr. Morakot Tanticharoen, Director General of the National Center for Genetic Engineering and Biotechnology, Thailand.

Topics discussed in the conference include: ethical, legal, and social implications (ELSI) of medical, food, and crop biotechnology; public and private sector partnerships; intellectual property protection of modern biotechnology; and biodiversity and biotechnology. 

Biolaw 2002 was organized by Dr. Tanit Changthavorn of the Department of Business Development and Biolaw, National Center for Genetic Engineering and Biotechnology, in coordination with the Southeast Asia Network on IP/TT Management. ISAAA co-sponsored this activity.

For further information on the highlights of the conference, please contact Dr. Changthavorn at business@biotec.or.th  


For more information, email Dr. Swapan Datta at s.data@cgiar.org 




ANNOUNCEMENTS

NEW K SHEET

A new K Sheet, "Emerging Technologies Critically needed in Africa" is available. It is a summary of the report from the United Nations Economic Commission for Africa, which was released during the World Summit. It is available at http://www.isaaa.org/kc/Services.htm. 


VIRTUAL EXHIBIT OF BANANA PROJECT

The Kenya TC Banana Project of ISAAA is on the virtual exhibit. The project entitled "Biotechnology to Benefit Small-Scale Banana Producers in Kenya" was developed in response to the rapid decline in banana production in Kenya over the last 20 years. This decline was due to infestation of the nation's banana orchards with pests and diseases, together with widespread soil degradation. View it at http://www.virtualexhibit.net/new/globalShowcaseTemplate.php?project_id=295&region
_id=4&industry_id=3
 


INTERNATIONAL CONFERENCE ON TECHNOLOGY IN SUSTAINABLE AGRICULTURE

CropLife Asia, in association with the International Service for the Acquisition of Agri-biotech Applications, and International Rice Research Institute, among others, is jointly sponsoring an international conference "More People, Less Land: Technology's Role in Sustainable Agriculture in Asia" on November 5-6, 2002 in Bangkok, Thailand.

This conference will present solid, science-based information that emphasizes the role that technologies can play in sustainable agricultural development. Myths and fallacies will be addressed, and the effects on real people will be highlighted. 

More details on the conference are available at http://www.croplifeasia.org. download registration form from http://www.croplifeasia.org/temp/mpll_rego_back.pdf 


INTERNATIONAL CONFERENCE ON S&T ETHICS

An international conference on Ethics of Science and Technology will be held from October 19-21, 2002 at Alexandria, Egypt. The four themes are: (i) Bioethics, human health and reproduction; (ii) Food, Agriculture, and GMOs; (iii) Energy and Climate; and (iv) Informatics, Communications and the Internet. For more information, go to http://www.bibalex.org/MainFrames.asp?LangID=1&Facility
ID=249&Type=5
  


RICE GENE MACHINE WORKSHOP

An international workshop entitled "Towards Building a Rice Gene Machine" will be held at the Optus Lecture Theatre, Discovery, CSIRO Black Mountain, Corner of Clunies Ross St and Barry Dr, Canberra, Australia on 11-12 November 2002. CSIRO Plant Industry is organizing this workshop with partial funding from the Australian Government Department of Education, Science and Training's Frontiers of S&T Missions and Workshops component of the Innovation Access Program, administered by the Australian Academy of Technological Sciences and Engineering. Rural Industries and Research Development Corporation (RIRDC), the NSW Agricultural Genomics Centre, CRC for Sustainable Rice Production and Embassy of France are also financially supporting this event. Several other embassies and agencies are also expected to contribute. For more information, visit the workshop website at http://www.pi.csiro.au/grgm02/home.htm.

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