Crop Biotech Update

A weekly summary of world developments in agri-biotech for developing countries, produced by the Global Knowledge Center on Crop Biotechnology, International Service for the Acquisition of Agri-biotech Applications SEAsiaCenter (ISAAA), and AgBiotechNet

January 10, 2003

In This Issue:

Developing Countries and Biotech Regulations
RR Fodder Beets Improve Biodiversity
Australia Gears Up Legume Research
Monsanto Receives Clearance for GM Cotton
Biotech: New Challenge to Thai Business Sector
Announcements:
Zambia Completes GM Guidelines
New Journal: Environmental Biosafety Research
Potential of Plant Biotech Widens
GE Proceedings Off the Press
"Jumping Genes" in Rice Identified
Biotech Winter Symposium

DEVELOPING COUNTRIES AND BIOTECH REGULATIONS

Developing countries have to address regulatory issues if they want to benefit from biotechnology. When the Cartagena Protocol comes into force, according to Julian Kinderlerer of the Sheffield Institute of Biotechnological Law and Ethics, University of Sheffield, United Kingdom, countries have to set in place legal and administrative systems to ensure that they are able to deal with both exports and imports of living modified organisms. If a scientific infrastructure to produce varieties adapted for their environment is not in place, the development of the capacity will take much longer.

Kinderlerer indicates the following systems that countries need to be instituted to ensure that any living modified organisms are used safely:

  • A system for receiving notifications about the intended introduction of a living modified organisms.
  • Specific systems for different uses, i.e. a product to be used only for food and feed versus those instituted with organisms that are intended to be released into the environment.
  • The administrative system must examine the dossier submitted by an applicant to ensure completeness.
  • The Government either performs or audits a risk assessment based on information in the dossier. In either case a system must be set up for scientific oversight of the dossiers received.
  • Systems must allow public and stakeholder comment to be considered.
  • A system for evaluating the risk assessment and/or the audit report and any public comments.

The full paper is available at http://www.unep.ch/biosafety/BTregulationJK.pdf


AUSTRALIA GEARS UP LEGUME RESEARCH

The Centre for Integrative Legume Research has been set-up in Australia to provide top rate legume research. Based at the University of Queensland in Brisbane, it combines the collaborative efforts of four premier research universities in Australia, namely the University of Queensland, University of Melbourne, The University of Newcastle and the Australian National University in Canberra.

The Centre's director, Peter M. Gresshoff, says the Queensland Premier, Mr. Peter Beattie, as well as the University of Queensland provided funds. The Australian Research Council allots A$10 million over the 5 year time span, while the University of Queensland and the State of Queensland will allot over A$1.2 M per year.

The Centre will conduct research on the systems biology of plant development and the coupling of genetic and metabolic processes to allow plant growth. It will complement the predominantly cereal-based research of the Australian Plant Functional Genomics Centre in Adelaide. This complementation will enable a better understanding of the abilities of plants in agricultural and ecological systems.

For more information email Peter Gresshoff at p.gresshoff@botany.uq.edu.au


BIOTECH: NEW CHALLENGE TO THAI BUSINESS SECTOR

The Nation Multimedia Group recently held a panel discussion entitled "Challenges and Opportunity for Biotechnology Business." During the discussion, the panelists stated that biotechnology presents a new challenge for the Thai business sector "and that the commercial sector seeks more support from the government to help local firms commercialize their products." Another point stressed was the need for government to clearly define specific areas of biotechnology where Thailand could compete globally.

The panel members called biotechnology as "a key technology trend," and have affirmed that the Thai government has agreed that biotechnology is one of three technology sectors essential to the country's development. The other two sectors mentioned were information and communication, and nanotechnology.

Biotechnology was also seen to have the potential to give entrepreneurs high value on their investments. According to the panelists, more government support is needed to boost biotechnology development in order to inspire local researchers and business entrepreneurs to join the field. At present, local businesses involved in biotechnology "lag in technological standards, facilities and human resources, as well as funding, thus limiting business opportunities."

The panel members were: Pongsak Nantawannakul, general manager of Agri Nature; Morakot Tanticharoen, director of the National Centre for Genetics and Biotechnology (Biotec); Yongyuth Yuthawong, president of the Thai Academy of Science and Technology Foundation; and Professor Sirirurg Songsivilai, director of the Cellular and Molecular Immunology at the Faculty of Medicine at Siriraj Hospital.

The full article is in http://www.nationmultimedia.com/page.arcview.php3?clid=6&id=71837&usrsess=1


ZAMBIA COMPLETES GM GUIDELINES

Abel Chambeshi, Minister of Science and Technology, announced that the Zambian government has completed its proposed guidelines on genetically modified (GM) food. The guidelines will be submitted to the Cabinet where it will hopefully be endorsed into law.

According to the Integrated Regional Information Networks (IRIN) which is part of the United Nations Office for the Coordination of Humanitarian Affairs, the guidelines are expected to fill a legislative void on the controversial subject. In particular, they were drawn up after President Levy Mwanawasa banned the import of GM food aid in 2002. The ban and the subsequent order to withdraw in-country stocks left food relief agencies cutting rations and finding alternate food sources for about 2.9 million people.

Go to http://www.irinnews.org/report.asp?ReportID=31628&SelectRegion=Southern_Africa&Select
Country=MALAWI-ZAMBIA
for the full article.


POTENTIAL OF PLANT BIOTECH WIDENS

Progress in research has encouraged a massive surge in plant biotechnology which is currently changing the vision of crop production and protection. So says Dominique Job of Bayer CropScience in France. In a paper "Plant Biotechnology in Agriculture" published in the international journal Biochimie, Job says that the evolution of transformation and breeding techniques have enabled researchers to respond to criticisms raised against transgenic plants in agriculture.

Job adds that technologies enable "us to envisage the feasibility of improving the nutritional conditions for animal and humans (yield increase, correction of nutritional deficiency, elimination of antinutritional components, vitamin intake) and health (protein and enzymes manufacture, vaccinal plants), to encourage the arrival of multiple new industry-oriented products and to produce crops that work in greater harmony with the environment in terms of their water requirements, pesticides, and fertilizers".

Job concludes that the finalization of new breeding methods, not based on the use of anitibiotics or herbicides, and the transformation of plastids provide examples that demonstrate a positive influence on the social debate surrounding their development". All that remains, Job asserts, is "to thoroughly evaluate the environmental impact of these transgenic crops".

The full paper is available online at http://www.sciencedirect.com


"JUMPING GENES" IN RICE IDENTIFIED

A collaborative research between US and Japanese researchers have identified the first active DNA transposons in rice or "jumping genes". They have also discovered the first active "miniature inverted-repeat transposable element" or MITE of any organism.

The work involved researchers at the University of Georgia, Cornell and Washington University in the USA and National Institute of Agrobiological Resources, National Institute for Basic Biology, Tokyo Metropolitan University, University of Tokyo, Kyoto University and Kinki University in Japan. Three papers are published in the Jan. 9, 2003 edition of the journal Nature.

Rice (Oryza sativa), an important food crop worldwide, has the smallest genome size of all cereals at 430 million base pairs of DNA. About 40 percent of the rice genome comprises repetitive DNA that does not code for proteins and thus has no obvious function for the plant. Much of this repetitive sequence appears to be transposons similar to MITEs. But like most genomes studied to date, including the human genome, the function of this highly repeated so-called "junk DNA" has been a mystery. The discovery of active transposons in rice provides startling new insights into how genomes change and what role transposons may play in the process.

The research findings will help researchers unravel the events leading to the origin, spread, and disappearance of miniature transposons. MITEs make up a large part of the non-coding DNA in plant genomes. Through studies of transposons such as MITEs, researchers will begin to understand the impact of so-called "junk DNA" on the dynamic structure and function of the genomes of all organisms.

Visit http://www.nsf.gov/od/lpa/news/03/pr0303.htm for additional details.


RR FODDER BEETS IMPROVE BIODIVERSITY

Roundup Ready treatments in fodder beets "may result in significant improvements of weed flora and arthropod fauna during June and early July" as compared to conventionally treated beet herbicide plots. This was the major finding discussed in the National Environment Research Institute's Technical Report entitled "Biodiversity in Glyphosate Tolerant Fodder Beet Fields," by Beate Strandberg and Marianne Bruus Pedersen of the Department of Terrestial Ecology, National Environmental Research Institute in Denmark.

The results showed that environmental benefits can be achieved if the recommended label applications of Roundup Ready are followed, or if herbicide applications are further delayed. Another observation was that the production of weed seeds was reduced or entirely lacking. This implies that the "availability of seeds as food for the birds" may be affected. Significant changes in weed flora could also occur.

Further studies on "the effects over several seasons in relevant crop rotations" are needed in order to determine the long-term consequences of transgenic herbicide tolerant crops on biodiversity.

The full technical report of the National Environmental Research Institute is available at http://www.dmu.dk/1_viden/2_Publikationer/3_fagrapporter/rapporter/FR410.pdf


MONSANTO RECEIVES CLEARANCE FOR GM COTTON

Monsanto announced that it has received full U.S. regulatory clearance for its Bollgard II insect-protected cotton technology. Cotton producers in the US will have limited access to cotton seed containing this technology for the 2003 planting season.

Robb Fraley, Monsanto's Chief Technology Officer, said that Bollgard II is the second-generation of insect-protected cotton developed by the company. It contains two different insect-control genes, compared to the single insect-control gene in its predecessor Bollgard.

Visit http://www.monsanto.com/monsanto/layout/media/02/12-23-02.asp for the full report.


ANNOUNCEMENTS:

New Journal: Environmental Biosafety Research

A new interdisciplinary journal, Environmental Biosafety Research, the official journal of the International Society for Biosafety Research, has just been launched. The new journal aims to provide a single forum for the reporting and discussion of such issues as ecological studies of the impact of novel organisms; studies of their interactions with pests and pathogens; food and feed safety evaluation; impact of novel organisms on agronomy and farming practice, effect on microbial populations and assessment of horizontal gene flow.

The initial copy is available free of charge at http://www.edpsciences.org/ebr. For additional information send email to ebr@versailles.inra.fr


GE Proceedings Off the Press

Genetic Engineering and the Intrinsic Value and Integrity of Animals and Plants - Proceedings of a Workshop at the Royal Botanic Garden, Edinburgh, UK is now available. Summary and full details of how to order are at: http://www.anth.org/ifgene/2002.htm


Biotech Winter Symposium

The 2003 Miami Nature Biotechnology Winter Symposium will be held February 1-5, 2003 at Miami Beach Florida, USA. This year's theme is 50 Years On: From the Double Helix to Molecular Medicine.

James D. Watson and Francis Crick are the Symposium's Distinguished Service Awardees for 2003. The opening keynote lecture will be presented by James Watson, entitled: Finding the Double Helix.

For more information, visit http://www.med.miami.edu/mnbws and register on-line.

 

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